My doctoral research focuses on the environmental drivers and economic impacts of infectious disease. The work I conduct is largely model-based; I develop in the versatile Julia programming language. Specifically, my efforts complement the laboratory creation of genetically modified disease vectors by simulating their real-world use as public health interventions.
The case studies I explore address deadly threats like Zika and malaria under the evolving reality of climate change. I hope for this research to help reduce mosquito-borne illnesses and augment scientific understanding of genetic tools, including CRISPR-Cas9 systems. Advisors Dr. John Marshall (molecular biology, epidemiology), Dr. David Anthoff (economics, scientific computing), and Dr. Lara Kueppers (ecology, climate dynamics) guide my work in these areas.
Stoudt, S.†; Vásquez, V.N.†; Martinez, C. “Principles for Data Analysis Workflows.” PLOS Computational Biology (2021). †Equal contribution [link]
Marshall, J.M.; Vásquez, V.N. “Field trials of gene drive mosquitoes: Lessons from releases of genetically sterile males and Wolbachia-infected mosquitoes.” In B.K. Tyagi (Ed.), Eco-Bio-Social Considerations for the Safe Application of Genetically Modified Vectors to Control Malaria and Dengue (2020). Springer-Nature, in press. [link]
Hogg, C.J.; Lea, M.A.; Gual, M.S.; Vásquez, V.N.; Payo-Payo, A.; Parrott, M.; Santos, M.M.; Shaw, J.; Brooks, C. “Protect the Antarctic Peninsula - Before It’s Too Late.” Nature (2020). [link]
Cheung, C.; Gamez, S.; Carballar-Lejarazú, R.; Ferman, V.; Vásquez, V.N.; Terradas, G.; Schairer, C.E.; Marshall, J.M.; Akbari, O.S.; Bloss, C.S. “Translating Gene Drive Science to Include Linguistically Diverse Populations in Community and Stakeholder Engagement.” Global Public Health (2020). [link]
Scovronick, N.; Vásquez, V.N.; Errickson, F.; Dennig, F.; Hajat, S.; Gasparrini, A.; Spears, D.; Budolfson, M.B. “Human Health and the Social Cost of Carbon: A Primer and Call to Action.” Epidemiology (2019). [link]
Moore, F. C.; Rising, J.; Lollo, N.; Springer, C.; Vásquez, V.N.; Dolginow, A.; Anthoff, D.; Hope, C. “Mimi-PAGE: An Open-Source Implementation of the PAGE09 Integrated Assessment Model.” Nature Scientific Data (2018). [link]
Melnick, R.†; Vásquez, V.N.†, Kanarek, A.; Lloyd, A.L.; Marshall, J.M.; Teem, J.L; Roberts, A. “Computational Models: Essential Tools for the Risk Assessment of Gene Drive Systems.” Submitted, Integrated Environmental Assessment and Management (2021). †Equal contribution
Hunter-Zink, H.; de Siqueira, A.; Vásquez, V.N.; Barnes, R.; Martinez, C. “Ten Simple Rules on Writing Clean and Well-Tested Open-Source Scientific Software.” Submitted, PLOS Computational Biology (2021).
Cromar, K.; Howard, P.; Vásquez, V.N.; Anthoff, D. “Health Impacts of Climate Change as Contained in Economic Models Estimating the Social Cost of Carbon Dioxide.” Submitted, GeoHealth (2021).
Vásquez, V.N. “Optimizing Genetic-Based Public Health Interventions.” Invited presentation to the Data Science Consortium, Michigan Institute for Data Science (MIDAS), University of Michigan, October 2020. [link]
Vásquez, V.N. “Novel Genetic Constructs and Sensitivity to Environmental Change: Implications for Disease Vectors.” Poster presented at Ecological Society of America (ESA) Annual Meeting, August 2020.
Vásquez, V.N. “Exploring Disease Vector Dynamics Under Environmental Change.” Presentation for JuliaCon2020, July 2020. [link]
Vásquez, V.N.; Marshall, J.M. “Informing Risk Assessment with the Mosquito Gene Drive Explorer (MGDRivE).” Webinar presentation for the Gene Drive Modeling Conference Seminar Series conducted by the International Life Sciences Institute (ILSI) Research Foundation, May 2019. [link]
Vásquez, V.N.; Rodriguez, M.C.; Pawling, K.T. “Climate Change: Towards the Future.” Panel presentation at Latinx and the Environment Summit, April 2019.
Sánchez, H.M.C.; Bennett, J.B.; Wu, S.L.; Vásquez, V.N.; Marshall, J.M. “MGDrivE: A simulation framework for gene drive in spatially explicit mosquito populations, and its application to threshold-dependent systems.” Poster presented at American Society of Tropical Medicine and Hygiene (ASTMH), October 2018.
Sánchez, H.M.C.; Bennett, J.B.; Wu, S.L.; Vásquez, V.N.; Marshall, J.M. “MGDrivE: A simulation framework for gene drive releases in spatially explicit mosquito populations, and its application to mosquito-borne disease control.” Poster presented at Infectious Disease Dynamics Conference (IDDConf) by the Centre for the Mathematical Modelling of Infectious Diseases, September 2018. [link]
Vásquez, V.N. “Using Twitter to Inform Robust Decision Making for Divergent Groups.” Presentation to domestic RAND Corporation offices, August 2017.
Wara, M.; Vásquez, V.N.; Larsen, K. “Climate Policy.” Panel presentation at the Berkeley Energy and Resources Collaborative (BERC) Energy Summit, February 2016.